The main reasons why a 10-day-old kitten might suddenly stop nursing are as follows.

1) Physical Illness: If your kitten has a physical illness, it will feel unwell and refuse to nurse.
2) Environmental Changes: Generally speaking, kittens will feel uncomfortable in a relatively unfamiliar environment, which can affect their eating habits.
3) Digestive problems: Kittens have very delicate digestive systems, and they may refuse to eat if they eat too much.