Domestic shorthair cats cannot be kept without vaccinations. Firstly, regular vaccinations help prevent feline panleukopenia, feline calicivirus, and feline herpesvirus, thus protecting their health and potentially extending their lifespan. Secondly, even if the cat doesn't go outside often, its owner can easily bring viruses home, leading to indirect infection. Viral diseases have a high mortality rate, so timely vaccinations are highly recommended. 
Precautions for vaccinating domestic shorthair cats:
1. Cats should not be bathed immediately after vaccination. Because their resistance is relatively weak after vaccination, it is best to wait a week or half a month before bathing them to avoid them getting cold or frightened and becoming sick.
2. After vaccination, keep your cat warm and avoid taking it outside to prevent it from getting infected with bacteria or viruses.
3. Pay attention to feeding after vaccination. Cats may experience a loss of appetite after vaccination. Do not force them to eat during this period. Give them time to recover. Avoid feeding them overly greasy food.
