Why does a cat suddenly open its mouth and look confused when smelling something?
When a cat suddenly opens its mouth in confusion while smelling something, it may be because the smell is unfamiliar or irritating to it, making it feel curious, alert, or uncomfortable.
Cats have an extremely sensitive sense of smell; their noses contain a large number of olfactory receptors, making them highly sensitive to odors. When cats smell unfamiliar scents, they may exhibit different reactions. One common reaction is opening their mouths in a confused manner, which usually indicates that the cat is either curious or wary of the scent. 
For example, when a cat smells the aroma of a new food, it may open its mouth in confusion, trying to figure out where the smell is coming from and whether it is safe. Similarly, if a cat smells a strong odor, such as perfume, cleaning agents, or other chemicals, it may also open its mouth in confusion because the smell is too strong for its nose.
In addition, cats may exhibit other behavioral responses when they smell certain odors, such as sneezing, shaking their heads, or avoiding the smell. These could all indicate that the cat is uncomfortable with or uninterested in the odor.
In short, when a cat suddenly opens its mouth in confusion while sniffing something, it could be because it is curious, alert, or uncomfortable with that smell. As owners, we should pay attention to our cats' reactions and try to avoid exposing them to overly stimulating or harmful odors.