There could be several reasons why your cat meows when you're not in the room. Here are some common causes and suggestions:
1. Loneliness and Separation Anxiety: Cats are social animals and need interaction and companionship from people. When cats feel lonely or separated, they may meow to get attention and comfort. Before you leave the room, make sure to provide your cat with enough interaction and attention, such as playing, petting, or talking to them. Additionally, provide some toys and activities to entertain and stimulate them when you are not around.
2. Hunger or thirst: Cats may meow to indicate they need food or water. Make sure to provide your cat with plenty of food and fresh water before leaving the room to meet their needs.

3. Anxiety or Fear: Cats may meow because they feel anxious or afraid. This could be caused by external noise, strangers, other animals, or changes in the environment. Providing a safe, quiet, and undisturbed environment can help reduce anxiety and fear.
4. Physiological Needs: Cats may need their physiological needs met, such as using the litter box. Ensure the litter box is clean and easily accessible.